E2F7.H14INVITRO.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	E2F7.H14INVITRO.0.S.C
Gene (human)	E2F7 (GeneCards)
Gene synonyms (human)
Gene (mouse)	E2f7
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	17
Consensus	ndWTTTGGCGGGAAWdn
GC content	45.57%
Information content (bits; total / per base)	22.353 / 1.315
Data sources	HT-SELEX
Aligned words	2467
Previous names	E2F7.H12INVITRO.0.S.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.736	0.773	0.683	0.708	0.684	0.742	2.49	2.968	24.796	87.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	1.0	1.0	1.0	1.0	0.993	0.993
Non-Methyl HT-SELEX, 1 experiments	best	1.0	1.0	1.0	1.0	0.993	0.993

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Fork head/winged helix factors {3.3} (TFClass)
TF family	E2F {3.3.2} (TFClass)
TF subfamily	E2F {3.3.2.1} (TFClass)
TFClass ID	TFClass: 3.3.2.1.7
HGNC	HGNC:23820
MGI	MGI:1289147
EntrezGene (human)	GeneID:144455 (SSTAR profile)
EntrezGene (mouse)	GeneID:52679 (SSTAR profile)
UniProt ID (human)	E2F7_HUMAN
UniProt ID (mouse)	E2F7_MOUSE
UniProt AC (human)	Q96AV8 (TFClass)
UniProt AC (mouse)	Q6S7F2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	E2F7.H14INVITRO.0.S.C.pcm
PWM	E2F7.H14INVITRO.0.S.C.pwm
PFM	E2F7.H14INVITRO.0.S.C.pfm
Threshold to P-value map	E2F7.H14INVITRO.0.S.C.thr
Motif in other formats
JASPAR format	E2F7.H14INVITRO.0.S.C_jaspar_format.txt
MEME format	E2F7.H14INVITRO.0.S.C_meme_format.meme
Transfac format	E2F7.H14INVITRO.0.S.C_transfac_format.txt
Homer format	E2F7.H14INVITRO.0.S.C_homer_format_0.001.txt E2F7.H14INVITRO.0.S.C_homer_format_0.0005.txt E2F7.H14INVITRO.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	802.75	378.75	695.75	589.75
02	810.0	224.0	783.0	650.0
03	841.0	27.0	81.0	1518.0
04	176.0	19.0	48.0	2224.0
05	34.0	13.0	21.0	2399.0
06	18.0	4.0	10.0	2435.0
07	1.0	44.0	2417.0	5.0
08	7.0	17.0	2439.0	4.0
09	2.0	2460.0	2.0	3.0
10	1.0	2.0	2460.0	4.0
11	1.0	22.0	2443.0	1.0
12	3.0	23.0	2436.0	5.0
13	2457.0	4.0	3.0	3.0
14	2367.0	7.0	85.0	8.0
15	1903.0	146.0	76.0	342.0
16	731.75	330.75	421.75	982.75
17	526.0	435.0	534.0	972.0

PFM

	A	C	G	T
01	0.325	0.154	0.282	0.239
02	0.328	0.091	0.317	0.263
03	0.341	0.011	0.033	0.615
04	0.071	0.008	0.019	0.901
05	0.014	0.005	0.009	0.972
06	0.007	0.002	0.004	0.987
07	0.0	0.018	0.98	0.002
08	0.003	0.007	0.989	0.002
09	0.001	0.997	0.001	0.001
10	0.0	0.001	0.997	0.002
11	0.0	0.009	0.99	0.0
12	0.001	0.009	0.987	0.002
13	0.996	0.002	0.001	0.001
14	0.959	0.003	0.034	0.003
15	0.771	0.059	0.031	0.139
16	0.297	0.134	0.171	0.398
17	0.213	0.176	0.216	0.394

PWM

	A	C	G	T
01	0.263	-0.486	0.12	-0.045
02	0.272	-1.007	0.238	0.052
03	0.309	-3.062	-2.009	0.899
04	-1.246	-3.385	-2.517	1.28
05	-2.845	-3.723	-3.294	1.356
06	-3.434	-4.644	-3.947	1.371
07	-5.345	-2.6	1.363	-4.488
08	-4.236	-3.486	1.373	-4.644
09	-5.053	1.381	-5.053	-4.828
10	-5.345	-5.053	1.381	-4.644
11	-5.345	-3.252	1.374	-5.345
12	-4.828	-3.211	1.371	-4.488
13	1.38	-4.644	-4.828	-4.828
14	1.343	-4.236	-1.962	-4.13
15	1.125	-1.431	-2.072	-0.587
16	0.17	-0.62	-0.379	0.465
17	-0.159	-0.348	-0.144	0.454

Standard thresholds

P-value	Threshold
0.001	-3.78134
0.0005	-1.93614
0.0001	1.95851