| Motif | CUX1.H14RSNP.2.P.C |
| Gene (human) | CUX1 (GeneCards) |
| Gene synonyms (human) | CUTL1 |
| Gene (mouse) | Cux1 |
| Gene synonyms (mouse) | Cutl1, Cux, Kiaa4047 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | C |
| Motif | CUX1.H14RSNP.2.P.C |
| Gene (human) | CUX1 (GeneCards) |
| Gene synonyms (human) | CUTL1 |
| Gene (mouse) | Cux1 |
| Gene synonyms (mouse) | Cutl1, Cux, Kiaa4047 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | C |
| Motif length | 19 |
| Consensus | WWdATKGWKKndYWbWKKh |
| GC content | 41.87% |
| Information content (bits; total / per base) | 12.274 / 0.646 |
| Data sources | ChIP-Seq |
| Aligned words | 1000 |
| Previous names | CUX1.H12RSNP.2.P.C |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (32) | 0.601 | 0.826 | 0.42 | 0.801 | 0.572 | 0.801 | 1.258 | 7.812 | 5.115 | 112.0 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.608 | 0.56 | 0.593 | 0.555 | 0.571 | 0.545 |
| best | 0.635 | 0.576 | 0.626 | 0.573 | 0.605 | 0.564 | |
| Methyl HT-SELEX, 1 experiments | median | 0.62 | 0.567 | 0.603 | 0.561 | 0.579 | 0.55 |
| best | 0.62 | 0.567 | 0.603 | 0.561 | 0.579 | 0.55 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.596 | 0.554 | 0.584 | 0.549 | 0.562 | 0.539 |
| best | 0.635 | 0.576 | 0.626 | 0.573 | 0.605 | 0.564 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.574 | 0.137 | 0.345 | 0.207 |
| batch 2 | 0.575 | 0.178 | 0.337 | 0.212 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-CUT {3.1.9} (TFClass) |
| TF subfamily | CUX {3.1.9.2} (TFClass) |
| TFClass ID | TFClass: 3.1.9.2.1 |
| HGNC | HGNC:2557 |
| MGI | MGI:88568 |
| EntrezGene (human) | GeneID:1523 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:13047 (SSTAR profile) |
| UniProt ID (human) | CUX1_HUMAN |
| UniProt ID (mouse) | CUX1_MOUSE |
| UniProt AC (human) | P39880 (TFClass) |
| UniProt AC (mouse) | P53564 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | CUX1.H14RSNP.2.P.C.pcm |
| PWM | CUX1.H14RSNP.2.P.C.pwm |
| PFM | CUX1.H14RSNP.2.P.C.pfm |
| Threshold to P-value map | CUX1.H14RSNP.2.P.C.thr |
| Motif in other formats | |
| JASPAR format | CUX1.H14RSNP.2.P.C_jaspar_format.txt |
| MEME format | CUX1.H14RSNP.2.P.C_meme_format.meme |
| Transfac format | CUX1.H14RSNP.2.P.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 676.0 | 111.0 | 58.0 | 155.0 |
| 02 | 722.0 | 22.0 | 53.0 | 203.0 |
| 03 | 163.0 | 130.0 | 575.0 | 132.0 |
| 04 | 871.0 | 88.0 | 23.0 | 18.0 |
| 05 | 85.0 | 11.0 | 97.0 | 807.0 |
| 06 | 57.0 | 16.0 | 674.0 | 253.0 |
| 07 | 58.0 | 88.0 | 834.0 | 20.0 |
| 08 | 805.0 | 73.0 | 47.0 | 75.0 |
| 09 | 58.0 | 39.0 | 594.0 | 309.0 |
| 10 | 104.0 | 77.0 | 138.0 | 681.0 |
| 11 | 135.0 | 287.0 | 239.0 | 339.0 |
| 12 | 462.0 | 61.0 | 388.0 | 89.0 |
| 13 | 47.0 | 580.0 | 132.0 | 241.0 |
| 14 | 208.0 | 77.0 | 29.0 | 686.0 |
| 15 | 95.0 | 437.0 | 265.0 | 203.0 |
| 16 | 328.0 | 58.0 | 54.0 | 560.0 |
| 17 | 68.0 | 28.0 | 509.0 | 395.0 |
| 18 | 103.0 | 38.0 | 732.0 | 127.0 |
| 19 | 147.0 | 173.0 | 121.0 | 559.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.676 | 0.111 | 0.058 | 0.155 |
| 02 | 0.722 | 0.022 | 0.053 | 0.203 |
| 03 | 0.163 | 0.13 | 0.575 | 0.132 |
| 04 | 0.871 | 0.088 | 0.023 | 0.018 |
| 05 | 0.085 | 0.011 | 0.097 | 0.807 |
| 06 | 0.057 | 0.016 | 0.674 | 0.253 |
| 07 | 0.058 | 0.088 | 0.834 | 0.02 |
| 08 | 0.805 | 0.073 | 0.047 | 0.075 |
| 09 | 0.058 | 0.039 | 0.594 | 0.309 |
| 10 | 0.104 | 0.077 | 0.138 | 0.681 |
| 11 | 0.135 | 0.287 | 0.239 | 0.339 |
| 12 | 0.462 | 0.061 | 0.388 | 0.089 |
| 13 | 0.047 | 0.58 | 0.132 | 0.241 |
| 14 | 0.208 | 0.077 | 0.029 | 0.686 |
| 15 | 0.095 | 0.437 | 0.265 | 0.203 |
| 16 | 0.328 | 0.058 | 0.054 | 0.56 |
| 17 | 0.068 | 0.028 | 0.509 | 0.395 |
| 18 | 0.103 | 0.038 | 0.732 | 0.127 |
| 19 | 0.147 | 0.173 | 0.121 | 0.559 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.99 | -0.803 | -1.439 | -0.474 |
| 02 | 1.056 | -2.362 | -1.526 | -0.207 |
| 03 | -0.424 | -0.648 | 0.829 | -0.633 |
| 04 | 1.243 | -1.032 | -2.32 | -2.546 |
| 05 | -1.066 | -2.985 | -0.936 | 1.167 |
| 06 | -1.455 | -2.653 | 0.987 | 0.012 |
| 07 | -1.439 | -1.032 | 1.2 | -2.45 |
| 08 | 1.165 | -1.215 | -1.642 | -1.188 |
| 09 | -1.439 | -1.821 | 0.861 | 0.211 |
| 10 | -0.867 | -1.162 | -0.589 | 0.998 |
| 11 | -0.61 | 0.137 | -0.045 | 0.303 |
| 12 | 0.611 | -1.39 | 0.437 | -1.02 |
| 13 | -1.642 | 0.838 | -0.633 | -0.036 |
| 14 | -0.183 | -1.162 | -2.103 | 1.005 |
| 15 | -0.956 | 0.556 | 0.058 | -0.207 |
| 16 | 0.27 | -1.439 | -1.508 | 0.803 |
| 17 | -1.284 | -2.136 | 0.707 | 0.455 |
| 18 | -0.877 | -1.846 | 1.07 | -0.671 |
| 19 | -0.526 | -0.365 | -0.718 | 0.801 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.21056 |
| 0.0005 | 5.09936 |
| 0.0001 | 6.98061 |