MotifATF4.H14RSNP.1.S.B
Gene (human)ATF4
(GeneCards)
Gene synonyms (human)CREB2, TXREB
Gene (mouse)Atf4
Gene synonyms (mouse)Creb2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusdvMTGACGCAATvn
GC content46.15%
Information content (bits; total / per base)17.264 / 1.233
Data sourcesHT-SELEX
Aligned words643
Previous namesATF4.H12RSNP.1.S.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 7 (42) 0.909 0.959 0.912 0.96 0.975 0.992 5.524 6.635 758.101 1023.921
Mouse 2 (9) 0.779 0.847 0.775 0.844 0.908 0.965 4.049 4.796 513.469 683.553

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.767 0.72 0.648 0.636 0.579 0.584
best 0.878 0.794 0.934 0.855 0.961 0.898
Methyl HT-SELEX, 1 experiments median 0.866 0.765 0.909 0.82 0.814 0.768
best 0.866 0.765 0.909 0.82 0.814 0.768
Non-Methyl HT-SELEX, 5 experiments median 0.716 0.714 0.604 0.62 0.557 0.571
best 0.878 0.794 0.934 0.855 0.961 0.898

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 7.268 6.277 0.285 0.219
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyATF4-related {1.1.6} (TFClass)
TF subfamily {1.1.6.0} (TFClass)
TFClass IDTFClass: 1.1.6.0.1
HGNCHGNC:786
MGIMGI:88096
EntrezGene (human)GeneID:468
(SSTAR profile)
EntrezGene (mouse)GeneID:11911
(SSTAR profile)
UniProt ID (human)ATF4_HUMAN
UniProt ID (mouse)ATF4_MOUSE
UniProt AC (human)P18848
(TFClass)
UniProt AC (mouse)Q06507
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 7 human, 2 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01185.7597.75248.75110.75
02114.25159.25272.2597.25
03429.0156.058.00.0
040.00.00.0643.0
050.00.0643.00.0
06643.00.00.00.0
070.0410.00.0233.0
080.00.0643.00.0
090.0628.00.015.0
10643.00.00.00.0
11643.00.00.00.0
120.0168.016.0459.0
13289.0226.067.061.0
14180.75165.75195.75100.75
PFM
ACGT
010.2890.1520.3870.172
020.1780.2480.4230.151
030.6670.2430.090.0
040.00.00.01.0
050.00.01.00.0
061.00.00.00.0
070.00.6380.00.362
080.00.01.00.0
090.00.9770.00.023
101.00.00.00.0
111.00.00.00.0
120.00.2610.0250.714
130.4490.3510.1040.095
140.2810.2580.3040.157
PWM
ACGT
010.143-0.4910.433-0.368
02-0.337-0.0090.523-0.496
030.975-0.03-1.002-4.61
04-4.61-4.61-4.611.379
05-4.61-4.611.379-4.61
061.379-4.61-4.61-4.61
07-4.610.93-4.610.368
08-4.61-4.611.379-4.61
09-4.611.355-4.61-2.279
101.379-4.61-4.61-4.61
111.379-4.61-4.61-4.61
12-4.610.044-2.2211.043
130.5820.338-0.861-0.953
140.1160.030.195-0.461
Standard thresholds
P-value Threshold
0.001 -0.09089
0.0005 1.28831
0.0001 5.28364