| Motif | ATF4.H14RSNP.0.P.B |
| Gene (human) | ATF4 (GeneCards) |
| Gene synonyms (human) | CREB2, TXREB |
| Gene (mouse) | Atf4 |
| Gene synonyms (mouse) | Creb2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | ATF4.H14RSNP.0.P.B |
| Gene (human) | ATF4 (GeneCards) |
| Gene synonyms (human) | CREB2, TXREB |
| Gene (mouse) | Atf4 |
| Gene synonyms (mouse) | Creb2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 13 |
| Consensus | dvMTGATGMAAYh |
| GC content | 44.81% |
| Information content (bits; total / per base) | 14.748 / 1.134 |
| Data sources | ChIP-Seq |
| Aligned words | 303 |
| Previous names | ATF4.H12RSNP.0.P.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 7 (42) | 0.977 | 0.991 | 0.967 | 0.984 | 0.976 | 0.993 | 5.629 | 6.418 | 768.168 | 1027.602 |
| Mouse | 2 (9) | 0.928 | 0.976 | 0.912 | 0.961 | 0.912 | 0.969 | 4.287 | 5.05 | 524.921 | 697.886 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.743 | 0.705 | 0.644 | 0.625 | 0.575 | 0.577 |
| best | 0.923 | 0.836 | 0.921 | 0.854 | 0.943 | 0.859 | |
| Methyl HT-SELEX, 1 experiments | median | 0.923 | 0.836 | 0.921 | 0.854 | 0.831 | 0.793 |
| best | 0.923 | 0.836 | 0.921 | 0.854 | 0.831 | 0.793 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.723 | 0.693 | 0.611 | 0.623 | 0.56 | 0.574 |
| best | 0.834 | 0.73 | 0.909 | 0.803 | 0.943 | 0.859 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 15.332 | 10.481 | 0.328 | 0.272 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | ATF4-related {1.1.6} (TFClass) |
| TF subfamily | {1.1.6.0} (TFClass) |
| TFClass ID | TFClass: 1.1.6.0.1 |
| HGNC | HGNC:786 |
| MGI | MGI:88096 |
| EntrezGene (human) | GeneID:468 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:11911 (SSTAR profile) |
| UniProt ID (human) | ATF4_HUMAN |
| UniProt ID (mouse) | ATF4_MOUSE |
| UniProt AC (human) | P18848 (TFClass) |
| UniProt AC (mouse) | Q06507 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 7 human, 2 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | ATF4.H14RSNP.0.P.B.pcm |
| PWM | ATF4.H14RSNP.0.P.B.pwm |
| PFM | ATF4.H14RSNP.0.P.B.pfm |
| Threshold to P-value map | ATF4.H14RSNP.0.P.B.thr |
| Motif in other formats | |
| JASPAR format | ATF4.H14RSNP.0.P.B_jaspar_format.txt |
| MEME format | ATF4.H14RSNP.0.P.B_meme_format.meme |
| Transfac format | ATF4.H14RSNP.0.P.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 95.0 | 28.0 | 124.0 | 56.0 |
| 02 | 49.0 | 46.0 | 168.0 | 40.0 |
| 03 | 116.0 | 138.0 | 48.0 | 1.0 |
| 04 | 3.0 | 0.0 | 0.0 | 300.0 |
| 05 | 0.0 | 1.0 | 298.0 | 4.0 |
| 06 | 276.0 | 21.0 | 6.0 | 0.0 |
| 07 | 3.0 | 20.0 | 2.0 | 278.0 |
| 08 | 1.0 | 1.0 | 300.0 | 1.0 |
| 09 | 57.0 | 224.0 | 3.0 | 19.0 |
| 10 | 296.0 | 6.0 | 1.0 | 0.0 |
| 11 | 289.0 | 5.0 | 8.0 | 1.0 |
| 12 | 6.0 | 104.0 | 40.0 | 153.0 |
| 13 | 82.0 | 135.0 | 38.0 | 48.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.314 | 0.092 | 0.409 | 0.185 |
| 02 | 0.162 | 0.152 | 0.554 | 0.132 |
| 03 | 0.383 | 0.455 | 0.158 | 0.003 |
| 04 | 0.01 | 0.0 | 0.0 | 0.99 |
| 05 | 0.0 | 0.003 | 0.983 | 0.013 |
| 06 | 0.911 | 0.069 | 0.02 | 0.0 |
| 07 | 0.01 | 0.066 | 0.007 | 0.917 |
| 08 | 0.003 | 0.003 | 0.99 | 0.003 |
| 09 | 0.188 | 0.739 | 0.01 | 0.063 |
| 10 | 0.977 | 0.02 | 0.003 | 0.0 |
| 11 | 0.954 | 0.017 | 0.026 | 0.003 |
| 12 | 0.02 | 0.343 | 0.132 | 0.505 |
| 13 | 0.271 | 0.446 | 0.125 | 0.158 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.223 | -0.964 | 0.486 | -0.296 |
| 02 | -0.426 | -0.487 | 0.786 | -0.622 |
| 03 | 0.42 | 0.591 | -0.446 | -3.459 |
| 04 | -2.858 | -3.99 | -3.99 | 1.362 |
| 05 | -3.99 | -3.459 | 1.356 | -2.654 |
| 06 | 1.279 | -1.236 | -2.341 | -3.99 |
| 07 | -2.858 | -1.281 | -3.114 | 1.287 |
| 08 | -3.459 | -3.459 | 1.362 | -3.459 |
| 09 | -0.278 | 1.072 | -2.858 | -1.329 |
| 10 | 1.349 | -2.341 | -3.459 | -3.99 |
| 11 | 1.325 | -2.485 | -2.102 | -3.459 |
| 12 | -2.341 | 0.312 | -0.622 | 0.694 |
| 13 | 0.078 | 0.57 | -0.672 | -0.446 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.05786 |
| 0.0005 | 4.259465 |
| 0.0001 | 6.74257 |